离合vicissitudes of life
背道而驰run counter to run in the opposite direction
本末倒置put the cart before the horse
笨鸟先飞the slow need to start early
必由之路the only way
闭关自守close the country to international intercourse
变本加厉be further intensified
变化无常chop and change fantasticality
变化无常chop and change fantasticality
别开生面having sth. New